Reprinted with permission from Ches...

Reprinted with permission from Chest. 2003;1 24:720-727 ?© 2003 American guild of Chest Physicians.

Background: The minute ventilation V^sub E^-carbon dioxide output V^sub CO2^ relationship has lately been demonstrated to have prognostic significance in me heart failure (HF) population. However, the course by which the V^sub E^/V^sub CO2^ incline is expressed has been inconsistent. Mefhods: individual hundred eighty-eight subjects, who had received diagnoses of HF underwent exercise testing. sum of two units V^sub E^/V^sub CO2^ slope calculations were made, united using exercise data prior to the ventilatory opening (VT), and one using all data points from peace to peak exercise. Four separate peak exercise V^sub E^/V^sub CO2^ incline calculations also were derived with unaveraged, 10- 30- and 60- ventilatory expired gas sampling intervals. Results: Although univariate Cox regression analysis demonstrated pre-VT and peak V^sub E^/V^sub CO2^ obliquity calculations to both be significant predictors of cardiac-related mortality and hospitalization (p

Copyright Cardiopulmonary Physical Therapy Journal Dec 2003

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