Reprinted with permission from Ches...

Reprinted with permission from Chest. 2003;1 24:75-82 ?© 2003 American corporation of Chest Physicians.

Study Objective: This investigation was designed to investigate the bulk of clinical muscle dysfunction in stable patients with COPD who were attending an out-patient pulmonary clinic compared with that of age-matched govern subjects without COPD. Oes/gn and Sub/'ecfs: Respiratory muscle and hand grip vigor steady-state O2 kinetics, and carcass composition were measured in 32 patients with COPD (19 women) [mean (?± SD) FEV^sub 1^ 38 ?± 11% predictedl and 36 age-matched command subjects (13 women). Kasu/fs: Measurements of handgrip force (mean, 97 ?± 32% v 106 ?± 26% predicted, respectively), maximal expiratory squeezing (mean, 57 ?± 33% v 61 ?± 22% predicted, respectively), steady-state O2 kinetics (mean r 72 ?± 34 s vs 78 ?± 37 s respectively) and steady-state CO2 kinetics (mean r 77 ?± 38 s vs 65 ?± 32 s respectively) at submaximal exercise were similar in patients and repress subjects. all the subjects, exclude for one female COPD patient, had a normal fat-free mass index (FFMI), although forward average the FFMI was lower in male patients (198 ?± 28) than in male rule subjects (23.0 ?± 2.8; p

Copyright Cardiopulmonary Physical Therapy Journal Dec 2003

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